The Walter and Eliza Hall Institute of Medical Research is one of Australia’s leading biomedical research organisations, with a national and international reputation for performing highly influential research.
TOWARDS BREAST CANCER PREVENTION IN HIGH-RISK WOMEN
Professor Jane Visvader and Professor Geoff Lindeman are pioneers in breast cancer research.
Since establishing a breast cancer research program at the Walter and Eliza Hall Institute of Medical Research they’ve made a series of landmark findings that have shaped our understanding of how breast cancers arise and how they could be prevented and treated.
Their breakthrough discoveries include identifying breast stem cells, which give rise to normal breast tissue, defining how normal breast growth is regulated, and how errors lead to breast cancer, and identifying the breast cells that are predisposed to becoming cancerous in women with BRCA1 gene mutations. These findings have led to the identification of an existing medication that might be repurposed as a breast cancer prevention drug for BRCA1 mutation carriers.
Together with an international team of researchers Professor Visvader and Professor Lindeman are now working towards clinical trials that will bring us a step closer to improving outcomes for BRCA carriers - stopping cancers before they begin without the need for surgery. There are many questions still to answer however, and funding is urgently required to continue this important work.
ABOUT the institute
The Walter and Eliza Hall Institute of Medical Research is one of Australia’s leading biomedical research organisations, with an international reputation for performing highly influential basic and translational research. The Institute is addressing some of the major health challenges of our time, with a focus on cancer, infection, inflammation, immune disorders, development and ageing. The Institute is at the forefront of research innovation, with a commitment to excellence and investment in research computing, advanced technologies and developing new medicines and diagnostics.
Breast and ovarian cancers can have a devastating impact on women, their family and friends, and the community. In recent years there have been encouraging improvements in the diagnosis and treatment of these cancers. However, further research is vital to understand the complexities of cellular growth and interactions that cause breast and ovarian cancers to arise.
The Walter and Eliza Hall Institute of Medical Research are dedicated to finding novel approaches for prevention and treatment of breast and ovarian cancer. Professors Geoff Lindeman and Jane Visvader are joint division heads of this breast cancer research laboratory, which is one of the most prestigious in Australia. They oversee a formidable team of researchers who have made landmark discoveries in the prevention and treatment of breast and ovarian cancers.
Your support would greatly accelerate this research, as well as supporting a promising young breast cancer researcher to join the team to undertake a research fellowship.